Quiz 🩺 Medicine
Psychopharmacology, Psychotherapy, and Neuropharmacology Quiz
Quiz generated from Psychopharmacology, Psychotherapy, and Neuropharmacology
Want to study this quiz?
Copy it to your free Gradiuz library and make it your own.
Question 1
Which dopamine pathway is associated with the positive symptoms of schizophrenia?
- Mesolimbic pathway
- Mesocortical pathway
- Nigrostriatal pathway
- Tuberoinfundibular pathway
Question 2
Extrapyramidal side effects of antipsychotics are primarily due to blockade of dopamine in which pathway?
- Nigrostriatal pathway
- Mesolimbic pathway
- Mesocortical pathway
- Tuberoinfundibular pathway
Question 3
Hyperprolactinemia caused by antipsychotics is due to blockade of dopamine in which pathway?
- Tuberoinfundibular pathway
- Nigrostriatal pathway
- Mesolimbic pathway
- Mesocortical pathway
Question 4
Which statement correctly compares typical and atypical antipsychotics?
- Both antagonize D2 receptors, but only atypical antipsychotics also antagonize 5HT2A receptors.
- Both antagonize 5HT2A receptors, but only typical antipsychotics also antagonize D2 receptors.
- Atypical antipsychotics antagonize D2 receptors but not 5HT2A receptors.
- Typical antipsychotics antagonize 5HT2A receptors but not D2 receptors.
Question 5
Which antipsychotic is considered the most efficacious known, and what is its primary side effect?
- Clozapine; agranulocytosis
- Haloperidol; tardive dyskinesia
- Chlorpromazine; hyperprolactinemia
- Fluphenazine; neuroleptic malignant syndrome
Question 6
Atypical (second-generation) antipsychotics are less likely to cause extrapyramidal symptoms and tardive dyskinesia than typical antipsychotics.
- True
- False
Question 7
Typical (first-generation) antipsychotics are hydrophilic and are rapidly removed from the body.
- True
- False
Question 8
The classic low-potency typical (first-generation) antipsychotic is __________.
Fill in the blank
Question 9
The classic high-potency typical (first-generation) antipsychotics are haloperidol and __________.
Fill in the blank
Question 10
Which set of symptoms is most consistent with neuroleptic malignant syndrome?
- Acute delirium, muscular rigidity, fever, and tachycardia
- Repetitive, involuntary, purposeless movements
- Inability to sit still, pacing in place, and distress
- Intermittent, sustained contractions of the tongue, face, neck, and back
Question 11
Which extrapyramidal symptom is described as an inability to sit still, pacing in place, and distress?
- Akathisia
- Dystonia
- Tardive dyskinesia
- Parkinsonism
Question 12
Neuroleptic malignant syndrome can occur at any time during the course of antipsychotic treatment.
- True
- False
Question 13
Which antipsychotic is considered the most efficacious?
- Clozapine (Clozaril)
- Risperidone (Risperdal)
- Aripiprazole (Abilify)
- Lurasidone (Latuda)
Question 14
What is the primary side effect of clozapine?
- Agranulocytosis
- Hyperprolactinemia
- Extrapyramidal symptoms
- Bipolar depression
Question 15
Clozapine carries five black box warnings.
- True
- False
Question 16
What is the major side effect of risperidone (Risperdal)?
- Hyperprolactinemia
- Agranulocytosis
- Sedation
- Partial D2 agonism
Question 17
Which pair of antipsychotics is least likely to cause extrapyramidal symptoms (EPS)?
- Clozapine and quetiapine
- Risperidone and olanzapine
- Haloperidol and fluphenazine
- Aripiprazole and lurasidone
Question 18
Which antipsychotic is the only one with partial agonism at D2 and 5-HT1A receptors?
- Aripiprazole (Abilify)
- Clozapine (Clozaril)
- Quetiapine (Seroquel)
- Risperidone (Risperdal)
Question 19
Aripiprazole is typically more efficacious than other atypical antipsychotics.
- True
- False
Question 20
Lurasidone (Latuda) is most commonly used to treat ______.
Fill in the blank
Question 21
Among atypical antipsychotics, which three are most likely to induce sedation?
- Quetiapine, olanzapine, and clozapine
- Aripiprazole, risperidone, and lurasidone
- Risperidone, aripiprazole, and ziprasidone
- Lurasidone, risperidone, and olanzapine
Question 22
The two antipsychotics least likely to cause EPS are clozapine and ______.
Fill in the blank
Question 23
Risperidone's major side effect is hyperprolactinemia.
- True
- False
Question 24
Approximately what percentage of patients taking clozapine develop agranulocytosis?
- 1%
- 25%
- 10%
- 50%
Made with Gradiuz
Turn any PDF into quizzes, flashcards and summaries - free.