Want to study this quiz?
Copy it to your free Gradiuz library and make it your own.
Question 1
Protein kinase A and protein kinase C phosphorylate which amino acid residues?
- Serine and threonine
- Tyrosine and histidine
- Lysine and arginine
- Serine and cysteine
Question 2
Kallmann syndrome classically causes infertility in males and amenorrhea in females. Which symptom may be present in both sexes?
- Anosmia
- Sensorineural deafness
- Retinitis pigmentosa
- Cerebellar ataxia
Question 3
Injury to which nerve causes loss of forearm flexion, difficulty supinating the forearm, and loss of sensation over the lateral forearm?
- Musculocutaneous nerve (C5-C7)
- Radial nerve
- Median nerve
- Ulnar nerve
Question 4
Which small-vessel vasculitis commonly presents with asymmetric multifocal neuropathy, typically causing wrist drop and foot drop?
- Eosinophilic granulomatosis with polyangiitis (EGPA)
- Giant cell arteritis
- IgA vasculitis
- Polyarteritis nodosa
Question 5
Esmolol is a long-acting oral class II antiarrhythmic used for chronic supraventricular arrhythmias.
- True
- False
Question 6
What is the normal plasma anion gap (in mEq/L)?
Fill in the blank
Question 7
Which apolipoprotein on chylomicron remnants is bound by the remnant receptor on the liver?
- ApoE
- ApoB-48
- ApoC-II
- ApoA-I
Question 8
Which immunoglobulin classes are decreased in ataxia-telangiectasia?
- IgA, IgG, and IgE
- IgA, IgM, and IgD
- IgG, IgD, and IgE
- IgM, IgG, and IgD
Question 9
A raised, discolored plaque with a waxy, 'stuck-on' appearance is characteristic of which skin disorder?
- Seborrheic keratosis
- Actinic keratosis
- Malignant melanoma
- Basal cell carcinoma
Question 10
Echinocandins exert their antifungal effect by inhibiting which enzyme?
- 1,3-beta-glucan synthase
- Cytochrome P450 14-alpha-demethylase
- Squalene epoxidase
- beta-glucanase
Question 11
Diffuse esophageal spasm classically appears as a 'corkscrew esophagus' on barium swallow.
- True
- False
Question 12
After entering smooth muscle cells through L-type Ca2+ channels, Ca2+ binds to ___.
Fill in the blank
Question 13
Which inheritance pattern is most common in hereditary spherocytosis?
- Autosomal dominant
- Autosomal recessive
- X-linked recessive
- Mitochondrial
Question 14
A patient's tremor is worst in the hands while they are resting and improves when reaching for an object. Which tremor type does this describe?
- Parkinson disease
- Essential tremor
- Physiologic tremor
- Cerebellar tremor
Question 15
A prepubertal boy has a right-sided varicocele that does not decrease when supine. What is the most appropriate next step?
- Abdominal ultrasound
- CT scan of the chest
- Observation for 6 months
- Testicular biopsy
Question 16
Which symptom is most characteristic of pelvic organ prolapse?
- Vaginal wall bulging and pressure worsened by Valsalva
- Sudden severe pelvic pain and fever
- Postcoital bleeding and weight loss
- A painless testicular mass
Question 17
What is the goal of uterine artery ligation?
- To decrease uterine blood flow and shrink fibroids
- To restore uterine blood flow in infertility
- To remove endometrial cysts
- To correct vaginal prolapse
Question 18
Supravalvular aortic stenosis is classically associated with which syndrome?
- Williams syndrome
- Marfan syndrome
- Down syndrome
- Noonan syndrome
Question 19
Williams syndrome is caused by a microdeletion of chromosome 12.
- True
- False
Question 20
Which combination is most consistent with sarcoidosis?
- Anterior uveitis, hilar lymphadenopathy, and erythematous nodular skin rash
- Malar rash, arthritis, and cytopenias
- Flushing, diarrhea, and wheezing
- Oral and genital ulcers with uveitis
Question 21
Down syndrome most often results from nondisjunction in the maternal oocyte during ___.
Fill in the blank
Question 22
Turner syndrome most often results from meiotic nondisjunction in which parent?
- Paternal meiosis
- Maternal meiosis I
- Maternal meiosis II
- Random in either parent equally
Question 23
Which defect causes congenital nephrogenic diabetes insipidus?
- Mutation in vasopressin V2 receptor or aquaporin 2 channel
- Deficiency of antidiuretic hormone
- Overactive vasopressin V2 receptor
- Excess renal aquaporin 2 channels
Question 24
In cystic fibrosis, bronchiectasis is primarily caused by neutrophil-mediated destruction of airway walls.
- True
- False
Made with Gradiuz
Turn any PDF into quizzes, flashcards and summaries - free.