Nick USMLE step 2CK/3 Part3 Quiz - Gradiuz

Nick USMLE step 2CK/3 Part3 Quiz

Quiz generated from Nick USMLE step 2CK/3 Part3

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Question 1

In Down syndrome maternal serum screening, which pattern of inhibin A and alpha-fetoprotein (AFP) is expected?

  • Increased inhibin A and decreased AFP
  • Decreased inhibin A and increased AFP
  • Increased inhibin A and increased AFP
  • Decreased inhibin A and decreased AFP
Question 2

A patient has prolonged paralysis after succinylcholine. Which condition best explains this?

  • Pseudocholinesterase deficiency
  • Acetylcholinesterase deficiency at the neuromuscular junction
  • CYP450 induction
  • Myasthenia gravis
Question 3

Which statement about infertility in cystic fibrosis and primary ciliary dyskinesia is correct?

  • Cystic fibrosis causes azoospermia from an absent vas deferens; primary ciliary dyskinesia causes immotile spermatozoa.
  • Cystic fibrosis causes immotile spermatozoa; primary ciliary dyskinesia causes an absent vas deferens.
  • Both conditions cause absolute sterility.
  • Both conditions cause ovarian failure.
Question 4

Which drug is a CYP450 inhibitor?

  • Cimetidine
  • Rifampin
  • Carbamazepine
  • Phenytoin
Question 5

DHEAS is produced only by the adrenal gland, and a high DHEAS level in a woman with hirsutism suggests an adrenal source.

  • True
  • False
Question 6

Which factor is the most important regulator of cerebral blood flow?

  • PaCO2
  • PaO2
  • Systemic pH
  • Heart rate
Question 7

A patient develops spontaneous gas gangrene caused by Clostridium septicum. Which underlying condition should be evaluated for?

  • Colon cancer
  • Gastric ulcer
  • Acute pancreatitis
  • Urinary tract infection
Question 8

Why is hCG used to trigger ovulation after follicle maturation with gonadotropins?

  • It binds LH receptors and has a long half-life, providing sustained LH-like stimulation.
  • It directly matures follicles without gonadotropins.
  • It suppresses FSH to prevent ovulation.
  • It prevents ovarian hyperstimulation syndrome.
Question 9

Statistical power is equal to 1 minus ____.

Fill in the blank

Question 10

How does Crohn disease of the terminal ileum promote calcium oxalate kidney stones?

  • Decreased fat absorption leaves more free oxalate to be absorbed.
  • Increased calcium absorption leads to hypercalciuria.
  • Decreased uric acid excretion causes uric acid stones.
  • Increased bile acid absorption causes oxalate stones.
Question 11

After complete loss of vitamin B12 intake or absorption, deficiency typically develops after how long?

  • 3 to 4 years
  • 3 to 4 days
  • 3 to 4 weeks
  • 3 to 4 months
Question 12

How is neonatal tetanus prevented?

  • Give Tdap to the mother at 27 to 36 weeks in every pregnancy and ensure hygienic delivery and cord care.
  • Give Tdap only in the first trimester of the first pregnancy.
  • Give the newborn Tdap before delivery.
  • Avoid vaccination during pregnancy and rely on cord care alone.
Question 13

A patient has an appendiceal abscess. What is the preferred management?

  • Image-guided percutaneous drainage with conservative treatment
  • Emergency appendectomy
  • Observation alone without antibiotics
  • Right hemicolectomy
Question 14

A patient who fell from a height has left shoulder pain and left upper quadrant tenderness with voluntary guarding, and is hemodynamically stable. What is the next step in management?

  • Abdominal CT
  • Shoulder radiography
  • Immediate exploratory laparotomy
  • Discharge with outpatient follow-up
Question 15

A 60-year-old man has 6 months of increasing urinary frequency with a nontender, firm, symmetrically enlarged prostate and no nodules on rectal examination. What is the next step?

  • Urinalysis
  • Prostate-specific antigen testing
  • Prostate ultrasonography
  • Cystoscopy
Question 16

Which finding requires incision and drainage rather than antibiotics alone?

  • A fluctuant mass
  • Purulent discharge without a collection
  • Erythema alone
  • A nonfluctuant area of induration
Question 17

The two most effective measures for preventing central line infection are preparing the skin with chlorhexidine and alcohol and ______ of the catheter when it is no longer needed.

Fill in the blank

Question 18

A postmenopausal woman has endometrial cells on a routine Pap smear with no cytologic abnormality. What is the next step?

  • Endometrial sampling
  • Repeat Pap smear in 1 year
  • No further evaluation needed
  • Hysterectomy
Question 19

Premenopausal women with benign endometrial cells and no cytologic abnormality on a screening Pap smear require endometrial sampling.

  • True
  • False
Question 20

A breastfeeding mother has deep stabbing breast and nipple pain, and her infant has a white coating on the tongue that is easily scraped off. What is the appropriate management?

  • Topical antifungal therapy for both mother and infant while continuing breastfeeding
  • Topical antifungal therapy for the infant only
  • Stop breastfeeding and start oral antibiotics for the mother
  • Reassurance only, since the findings are normal
Question 21

HIV testing is routinely recommended for all patients who develop a candidal infection.

  • True
  • False
Question 22

Which screening tests are recommended for all sexually active adolescents and adults at increased risk for sexually transmitted infections?

  • HIV testing plus NAAT for Chlamydia trachomatis and Neisseria gonorrhoeae
  • Syphilis serology plus herpes simplex virus PCR
  • HIV testing alone
  • NAAT for Chlamydia trachomatis alone
Question 23

Which mutation is associated with neuroblastoma?

  • n-myc mutation
  • c-myc mutation
  • BCR-ABL fusion
  • RAS mutation
Question 24

A 32-year-old sexually active woman has 2 weeks of postcoital pain and blood-tinged vaginal discharge. The cervix is tender to motion and bleeds when touched with a swab. What is the most likely diagnosis?

  • Chlamydia infection
  • Cervical trauma
  • Endometrial cancer
  • Bacterial vaginosis

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