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Question 1
Which class of calcium channel blockers is more selective for vascular smooth muscle?
- Dihydropyridines
- Non-dihydropyridines
- Both are equally selective
- Neither class is selective
Question 2
Which calcium channel blocker is the most selective for cardiac muscle?
- Verapamil
- Nifedipine
- Nimodipine
- Clevidipine
Question 3
Which calcium channel blocker is administered after a subarachnoid hemorrhage to prevent cerebral vasospasm?
- Nimodipine
- Verapamil
- Nicardipine
- Diltiazem
Question 4
Which antihypertensive class is protective against diabetic nephropathy in hypertensive patients?
- ACE inhibitors/ARBs
- Thiazide diuretics
- Beta blockers
- Dihydropyridine calcium channel blockers
Question 5
What is the mechanism of action of hydralazine?
- Increasing cGMP to cause smooth muscle relaxation
- Decreasing cGMP to cause smooth muscle contraction
- Blocking voltage-dependent L-type calcium channels
- Blocking beta-adrenergic receptors
Question 6
Which class of calcium channel blockers is associated with peripheral edema, gingival hyperplasia, and flushing?
- Dihydropyridines
- Non-dihydropyridines
- Both classes equally
- Neither class
Question 7
Non-dihydropyridine calcium channel blockers are associated with AV block.
- True
- False
Question 8
Hydralazine is contraindicated in angina or coronary artery disease because it can cause reflex tachycardia.
- True
- False
Question 9
Dihydropyridine calcium channel blockers are more selective for cardiac muscle than non-dihydropyridines.
- False
- True
Question 10
The names of dihydropyridine calcium channel blockers share the suffix ____.
Fill in the blank
Question 11
Which pair of calcium channel blockers is used in hypertensive urgency or emergency?
- Nicardipine and clevidipine
- Nifedipine and amlodipine
- Verapamil and diltiazem
- Nimodipine and verapamil
Question 12
In which condition may hydralazine be coadministered with a nitrate?
- Heart failure
- Primary hypertension
- Raynaud's phenomenon
- Atrial fibrillation
Question 13
Which adverse effect is associated with hydralazine?
- Reflex tachycardia
- Bradycardia
- Hyperkalemia
- Dry cough
Question 14
Which drug is a non-selective alpha and beta antagonist used to treat hypertensive emergency?
- Labetalol
- Metoprolol
- Phentolamine
- Nitroprusside
Question 15
Nitroprusside has a ___ duration of action.
Fill in the blank
Question 16
What is the main adverse effect of nitroprusside?
- Cyanide toxicity
- Hyperkalemia
- Lupus-like syndrome
- Reflex tachycardia
Question 17
Fenoldopam is a D1 receptor agonist used to treat hypertensive emergency.
- True
- False
Question 18
What is the mechanism of action of nitroprusside?
- Direct release of NO to increase cGMP
- Beta-1 receptor blockade
- Alpha-1 receptor blockade
- D1 receptor agonism
Question 19
Labetalol is a non-selective ___ and beta antagonist.
Fill in the blank
Question 20
Hydralazine's adverse effects include reflex tachycardia, lupus-like syndrome, and angina.
- True
- False
Question 21
Which drug directly releases nitric oxide to increase cGMP?
- Nitroprusside
- Hydralazine
- Labetalol
- Fenoldopam
Question 22
Which drug is a D1 receptor agonist?
- Fenoldopam
- Labetalol
- Nitroprusside
- Hydralazine
Question 23
Fenoldopam is a ___ receptor agonist.
Fill in the blank
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